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Your Position: Home > Protein > 5-HT2AR > 5HR-H55D3

Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Detergent)

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  • Synonym
    5-HT2A, HTR2A, HTR2, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A
  • Source
    Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag(5HR-H55D3) is expressed from Baculovirus-Insect cells. It contains AA Asp 2- Ala 265 & Gln 313 - Lys 403 (Accession # P28223-1 (S162K, M164W, S372N)).
    Predicted N-terminus: Asp
  • Molecular Characterization

    This protein carries flag tag at the N-terminus and polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 55.3 kDa.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.5, CHS with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
Bioactivity-ELISA
 5-HT2AR ELISA

Immobilized Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Cat. No. 5HR-H55D3) at 5 μg/mL (100 μL/well) can bind Anti-5-HT2AR Antibody (Cat. No. 5HR-H55D3) with a linear range of 0.02-0.625 μg/mL (QC tested).

  • Background
    This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepres.
  • Clinical and Translational Updates

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