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Your Position: Home > Protein > UBE1 > UB1-H5248

Human UBE1 / UBA1 Protein, His Tag

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  • Synonym
    A1S9T and BN75 temperature sensitivity complementing,A1S9T,A1ST,AMCX1,GXP1,MGC4781,POC20 centriolar protein homolog,POC20,Protein A1S9,SMAX2,UBA1,UBA1, ubiquitin-activating enzyme E1 homolog A,UBA1A,UBE1,UBE1A1S9,UBE1X,ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature sensitivitycomplementing),Ubiquitin-activating enzyme E1,Ubiquitinactivating Enzyme,Ubiquitin-activating Enzyme,ubiquitin-like modifier activating enzyme 1,ubiquitin-like modifier-activating enzyme 1
  • Source
    Human UBE1/UBA1, His Tag(UB1-H5248) is expressed from Baculovirus-Insect cells. It contains AA Ser 2- Arg 1058 (Accession # P22314-1).
  • Molecular Characterization
    UBE1 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 119.8 kDa. The protein migrates as 80-110 kDa under reducing (R) condition (SDS-PAGE).

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
SDS-PAGE
UBE1 SDS-PAGE

Human UBE1/UBA1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
  • Clinical and Translational Updates

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  • Number of Drugs in Clinical Trials:1 Details
  • Latest Research Phase:Phase 1 Clinical

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