Ifinatamab deruxtecan |
DS-7300; DS-7300a; MABX-9001a |
Phase 3 Clinical |
Daiichi Sankyo Co Ltd |
Solid tumours; Small Cell Lung Carcinoma |
Details
|
B7-H3 CAR-T cell therapy (Boyuan Runsheng Pharma) |
|
Phase 2 Clinical |
Boyuan Runsheng Pharma (Hangzhou) Co Ltd |
Solid tumours; Glioblastoma |
Details
|
Obrindatamab |
MGD-009; B7-H3 x CD3 |
Phase 2 Clinical |
Macrogenics Inc |
Mesothelioma; Carcinoma, Non-Small-Cell Lung; Melanoma; Thyroid Neoplasms; Sarcoma; Neuroblastoma; Neurofibrosarcoma; Prostatic Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Sarcoma, Synovial; Urinary Bladder Neoplasms; Wilms Tumor; Pancreatic Neoplasms; Colonic Neoplasms; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rhabdomyosarcoma |
Details
|
Vobramitamab duocarmazine |
MGC-018 |
Phase 2 Clinical |
Macrogenics Inc |
Liver Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Anus Neoplasms; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Carcinoma, Ovarian Epithelial; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Laryngeal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Small Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Melanoma |
Details
|
TAK-280 |
MVC-280; TAK-280 |
Phase 2 Clinical |
Maverick Therapeutics Inc |
Solid tumours; Neoplasms; Neoplasm Metastasis |
Details
|
4SCAR-276 |
4SCAR-276 |
Phase 2 Clinical |
Shenzhen Geno-Immune Medical Institute |
Solid tumours |
Details
|
IBI-3001 |
IBI-3001; IBI3001 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours |
Details
|
Allogenic B7H3-targeting CAR-γδT Cell Therapy |
QH104 Cell; QH-104 Cell |
Phase 2 Clinical |
Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated To Soochow University) |
Glioblastoma |
Details
|
IBI129 |
IBI-129; IBI129 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours |
Details
|
7MW3711 |
7-MW-3711; 7MW3711 |
Phase 2 Clinical |
Mabwell (Shanghai) Bioscience Co Ltd |
Solid tumours; Neoplasms |
Details
|
IBI334 |
IBI334; IBI-334 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours; Neoplasms |
Details
|
MHB088C |
MHB-088C |
Phase 2 Clinical |
Minghui Pharmaceutical Pty Ltd |
Solid tumours |
Details
|
DB-1311 |
DB-1311 |
Phase 2 Clinical |
|
Solid tumours; Neoplasm Metastasis |
Details
|
IBB-0979 |
IBB0979; IBB-0979 |
Phase 2 Clinical |
SunHo (China) BioPharmaceutical Co Ltd |
Solid tumours; Neoplasms |
Details
|
YL-201 |
YL-201; YL201 |
Phase 2 Clinical |
MediLink Therapeutics Co Ltd |
Solid tumours; Prostatic Neoplasms, Castration-Resistant |
Details
|
Fully Human B7H3 CAR-T Cells Therapy |
fhB7H3.CAR-Ts |
Phase 2 Clinical |
The Affiliated Hospital Of Xuzhou Medical University |
Ovarian Neoplasms; Carcinoma, Hepatocellular |
Details
|
CD-276-targeted Chimeric Antigen Receptor T Cell Therapy |
CD276 CAR-T |
Phase 2 Clinical |
Shenzhen University General Hospital |
Pancreatic Neoplasms |
Details
|
Enoblituzumab |
MGA-271; TJ271 |
Phase 2 Clinical |
Macrogenics Inc |
Carcinoma, Transitional Cell; Melanoma; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Osteosarcoma; Neuroblastoma; Sarcoma, Ewing; Prostatic Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Wilms Tumor; Carcinoma, Renal Cell; Desmoplastic Small Round Cell Tumor; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Solid tumours; Rhabdomyosarcoma; Head and Neck Neoplasms |
Details
|
HS-20093 |
HS20093; HS-20093 |
Phase 2 Clinical |
Shanghai Hansoh Biomedical Co Ltd |
Solid tumours; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Small Cell Lung Carcinoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Osteosarcoma |
Details
|
124I-omburtamab |
124I-8H9; 124I-8H9-(B7-H3) |
Phase 1 Clinical |
Memorial Sloan Kettering Cancer Center, Y-Mabs Therapeutics Inc |
Brain Neoplasms; Glioma |
Details
|
Mirzotamab clezutoclax |
ABBV-155 |
Phase 1 Clinical |
Abbvie Inc |
Solid tumours |
Details
|
SCRI-CARB7H3 |
SCRI-CARB7H3 |
Phase 1 Clinical |
Seattle Children'S Hospital |
Neuroblastoma; Choroid Plexus Neoplasms; Neoplasms, Germ Cell and Embryonal; Melanoma; Glioma; Diffuse Intrinsic Pontine Glioma; Neuroectodermal Tumors, Primitive; Sarcoma; Sarcoma, Clear Cell; Neurofibrosarcoma; Sarcoma, Ewing; Osteosarcoma; Retinoblastoma; Teratoma; Sarcoma, Synovial; Central Nervous System Neoplasms; Wilms Tumor; Diffuse midline glioma; Hepatoblastoma; Rhabdoid Tumor; Desmoplastic Small Round Cell Tumor; Carcinoma; Rhabdomyosarcoma; Medulloblastoma; Solid tumours; Ependymoma |
Details
|
CC-3 |
CC-3 |
Phase 1 Clinical |
Eberhard Karls University Of Tubingen, Germany |
Colorectal Neoplasms; Gastrointestinal Neoplasms |
Details
|
KT-095 |
KT-095 |
Phase 1 Clinical |
Nanjing Kati Medical Technology Co Ltd |
Solid tumours |
Details
|
EX-105 |
EX-105; EX105 |
Phase 1 Clinical |
Guangzhou Excelmab Inc |
Solid tumours |
Details
|
MGC-026 |
MGC026; MGC-026 |
Phase 1 Clinical |
Macrogenics Inc |
Prostatic Neoplasms, Castration-Resistant; Uterine Cervical Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Melanoma; Endometrial Neoplasms; Colorectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Ovarian Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Solid tumours |
Details
|
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University) |
|
Phase 1 Clinical |
Chulalongkorn University, King Chulalongkorn Memorial Hospital |
Brain Neoplasms; Diffuse Intrinsic Pontine Glioma |
Details
|
Autologous CAR-T Cells Targeting B7-H3(Unc Lineberger Comprehensive Cancer Center) |
|
Phase 1 Clinical |
Unc Lineberger Comprehensive Cancer Center |
Ovarian Neoplasms; Pancreatic Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Neoplasms; Breast Neoplasms |
Details
|
MT-027 |
MT-027 |
Phase 1 Clinical |
T-Maximum Pharmaceutical (Suzhou) Co Ltd |
Glioma |
Details
|
UTAA06 |
UTAA-06 |
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Leukemia, Myeloid, Acute |
Details
|
B7-H3 CAR T-cell therapy(Stanford University) |
B7-H3CART |
Phase 1 Clinical |
Stanford University |
Nervous System Diseases |
Details
|
TX103 CAR-T cell therapy(Fuzhou Tuoxin Tiancheng Biotechnology) |
|
Phase 1 Clinical |
Fuzhou Tuoxin Tiancheng Biotechnology Co Ltd |
Solid tumours; Glioma |
Details
|
EGFR/B7H3 CAR-T |
EGFR/B7H3 CAR-T |
Phase 1 Clinical |
Second Affiliated Hospital Of Guangzhou Medical University |
Triple Negative Breast Neoplasms; Lung Neoplasms |
Details
|
BAT-8009 |
BAT8009; BAT-8009 |
Phase 1 Clinical |
Bio-Thera Solutions Ltd |
Solid tumours |
Details
|
TAA-06 |
TAA06-UCAR-γδT; TAA-06 |
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Solid tumours; Neuroblastoma; Colorectal Neoplasms; Lung Neoplasms; Melanoma |
Details
|
XmAb-808 |
XmAb808 |
Phase 1 Clinical |
Xencor Inc |
Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung |
Details
|
Anti-CD276 CAR T-cell therapy (Persongen ) |
|
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Stomach Neoplasms; Small Cell Lung Carcinoma; Osteosarcoma; Neuroblastoma; Lung Neoplasms |
Details
|
B7-H3-targeting CAR-T cell therapy |
|
|
Beijing Tiantan Hospital, Capital Medical University |
|
Details
|
Ifinatamab deruxtecan |
DS-7300; DS-7300a; MABX-9001a |
Phase 3 Clinical |
Daiichi Sankyo Co Ltd |
Solid tumours; Small Cell Lung Carcinoma |
Details
|
B7-H3 CAR-T cell therapy (Boyuan Runsheng Pharma) |
|
Phase 2 Clinical |
Boyuan Runsheng Pharma (Hangzhou) Co Ltd |
Solid tumours; Glioblastoma |
Details
|
Obrindatamab |
MGD-009; B7-H3 x CD3 |
Phase 2 Clinical |
Macrogenics Inc |
Mesothelioma; Carcinoma, Non-Small-Cell Lung; Melanoma; Thyroid Neoplasms; Sarcoma; Neuroblastoma; Neurofibrosarcoma; Prostatic Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Sarcoma, Synovial; Urinary Bladder Neoplasms; Wilms Tumor; Pancreatic Neoplasms; Colonic Neoplasms; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rhabdomyosarcoma |
Details
|
Vobramitamab duocarmazine |
MGC-018 |
Phase 2 Clinical |
Macrogenics Inc |
Liver Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Anus Neoplasms; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Carcinoma, Ovarian Epithelial; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Laryngeal Neoplasms; Carcinoma, Squamous Cell; Carcinoma, Small Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Melanoma |
Details
|
TAK-280 |
MVC-280; TAK-280 |
Phase 2 Clinical |
Maverick Therapeutics Inc |
Solid tumours; Neoplasms; Neoplasm Metastasis |
Details
|
4SCAR-276 |
4SCAR-276 |
Phase 2 Clinical |
Shenzhen Geno-Immune Medical Institute |
Solid tumours |
Details
|
IBI-3001 |
IBI-3001; IBI3001 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours |
Details
|
Allogenic B7H3-targeting CAR-γδT Cell Therapy |
QH104 Cell; QH-104 Cell |
Phase 2 Clinical |
Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated To Soochow University) |
Glioblastoma |
Details
|
IBI129 |
IBI-129; IBI129 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours |
Details
|
7MW3711 |
7-MW-3711; 7MW3711 |
Phase 2 Clinical |
Mabwell (Shanghai) Bioscience Co Ltd |
Solid tumours; Neoplasms |
Details
|
IBI334 |
IBI334; IBI-334 |
Phase 2 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours; Neoplasms |
Details
|
MHB088C |
MHB-088C |
Phase 2 Clinical |
Minghui Pharmaceutical Pty Ltd |
Solid tumours |
Details
|
DB-1311 |
DB-1311 |
Phase 2 Clinical |
|
Solid tumours; Neoplasm Metastasis |
Details
|
IBB-0979 |
IBB0979; IBB-0979 |
Phase 2 Clinical |
SunHo (China) BioPharmaceutical Co Ltd |
Solid tumours; Neoplasms |
Details
|
YL-201 |
YL-201; YL201 |
Phase 2 Clinical |
MediLink Therapeutics Co Ltd |
Solid tumours; Prostatic Neoplasms, Castration-Resistant |
Details
|
Fully Human B7H3 CAR-T Cells Therapy |
fhB7H3.CAR-Ts |
Phase 2 Clinical |
The Affiliated Hospital Of Xuzhou Medical University |
Ovarian Neoplasms; Carcinoma, Hepatocellular |
Details
|
CD-276-targeted Chimeric Antigen Receptor T Cell Therapy |
CD276 CAR-T |
Phase 2 Clinical |
Shenzhen University General Hospital |
Pancreatic Neoplasms |
Details
|
Enoblituzumab |
MGA-271; TJ271 |
Phase 2 Clinical |
Macrogenics Inc |
Carcinoma, Transitional Cell; Melanoma; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Osteosarcoma; Neuroblastoma; Sarcoma, Ewing; Prostatic Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Ovarian Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Wilms Tumor; Carcinoma, Renal Cell; Desmoplastic Small Round Cell Tumor; Abdominal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Solid tumours; Rhabdomyosarcoma; Head and Neck Neoplasms |
Details
|
HS-20093 |
HS20093; HS-20093 |
Phase 2 Clinical |
Shanghai Hansoh Biomedical Co Ltd |
Solid tumours; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Small Cell Lung Carcinoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Osteosarcoma |
Details
|
124I-omburtamab |
124I-8H9; 124I-8H9-(B7-H3) |
Phase 1 Clinical |
Memorial Sloan Kettering Cancer Center, Y-Mabs Therapeutics Inc |
Brain Neoplasms; Glioma |
Details
|
Mirzotamab clezutoclax |
ABBV-155 |
Phase 1 Clinical |
Abbvie Inc |
Solid tumours |
Details
|
SCRI-CARB7H3 |
SCRI-CARB7H3 |
Phase 1 Clinical |
Seattle Children'S Hospital |
Neuroblastoma; Choroid Plexus Neoplasms; Neoplasms, Germ Cell and Embryonal; Melanoma; Glioma; Diffuse Intrinsic Pontine Glioma; Neuroectodermal Tumors, Primitive; Sarcoma; Sarcoma, Clear Cell; Neurofibrosarcoma; Sarcoma, Ewing; Osteosarcoma; Retinoblastoma; Teratoma; Sarcoma, Synovial; Central Nervous System Neoplasms; Wilms Tumor; Diffuse midline glioma; Hepatoblastoma; Rhabdoid Tumor; Desmoplastic Small Round Cell Tumor; Carcinoma; Rhabdomyosarcoma; Medulloblastoma; Solid tumours; Ependymoma |
Details
|
CC-3 |
CC-3 |
Phase 1 Clinical |
Eberhard Karls University Of Tubingen, Germany |
Colorectal Neoplasms; Gastrointestinal Neoplasms |
Details
|
KT-095 |
KT-095 |
Phase 1 Clinical |
Nanjing Kati Medical Technology Co Ltd |
Solid tumours |
Details
|
EX-105 |
EX-105; EX105 |
Phase 1 Clinical |
Guangzhou Excelmab Inc |
Solid tumours |
Details
|
MGC-026 |
MGC026; MGC-026 |
Phase 1 Clinical |
Macrogenics Inc |
Prostatic Neoplasms, Castration-Resistant; Uterine Cervical Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Melanoma; Endometrial Neoplasms; Colorectal Neoplasms; Sarcoma; Urinary Bladder Neoplasms; Ovarian Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Solid tumours |
Details
|
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University) |
|
Phase 1 Clinical |
Chulalongkorn University, King Chulalongkorn Memorial Hospital |
Brain Neoplasms; Diffuse Intrinsic Pontine Glioma |
Details
|
Autologous CAR-T Cells Targeting B7-H3(Unc Lineberger Comprehensive Cancer Center) |
|
Phase 1 Clinical |
Unc Lineberger Comprehensive Cancer Center |
Ovarian Neoplasms; Pancreatic Neoplasms; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Neoplasms; Breast Neoplasms |
Details
|
MT-027 |
MT-027 |
Phase 1 Clinical |
T-Maximum Pharmaceutical (Suzhou) Co Ltd |
Glioma |
Details
|
UTAA06 |
UTAA-06 |
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Leukemia, Myeloid, Acute |
Details
|
B7-H3 CAR T-cell therapy(Stanford University) |
B7-H3CART |
Phase 1 Clinical |
Stanford University |
Nervous System Diseases |
Details
|
TX103 CAR-T cell therapy(Fuzhou Tuoxin Tiancheng Biotechnology) |
|
Phase 1 Clinical |
Fuzhou Tuoxin Tiancheng Biotechnology Co Ltd |
Solid tumours; Glioma |
Details
|
EGFR/B7H3 CAR-T |
EGFR/B7H3 CAR-T |
Phase 1 Clinical |
Second Affiliated Hospital Of Guangzhou Medical University |
Triple Negative Breast Neoplasms; Lung Neoplasms |
Details
|
BAT-8009 |
BAT8009; BAT-8009 |
Phase 1 Clinical |
Bio-Thera Solutions Ltd |
Solid tumours |
Details
|
TAA-06 |
TAA06-UCAR-γδT; TAA-06 |
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Solid tumours; Neuroblastoma; Colorectal Neoplasms; Lung Neoplasms; Melanoma |
Details
|
XmAb-808 |
XmAb808 |
Phase 1 Clinical |
Xencor Inc |
Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Transitional Cell; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung |
Details
|
Anti-CD276 CAR T-cell therapy (Persongen ) |
|
Phase 1 Clinical |
Persongen Biotherapeutics (Suzhou) Co Ltd |
Stomach Neoplasms; Small Cell Lung Carcinoma; Osteosarcoma; Neuroblastoma; Lung Neoplasms |
Details
|
B7-H3-targeting CAR-T cell therapy |
|
|
Beijing Tiantan Hospital, Capital Medical University |
|
Details
|