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ROBO1

Brief Information

Name:Roundabout homolog 1
Target Synonym:DUTT1,Roundabout homolog 1,ROBO1,Roundabout Guidance Receptor 1,Deleted In U Twenty Twenty,Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila),Roundabout (Axon Guidance Receptor, Drosophila) Homolog 1,Roundabout, Axon Guidance Receptor, Homolog 1,H-Robo-1,SAX3,FLJ21882
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

RB1-HF2H7-Cell-based assay
 ROBO1 FACS

2e5 of Anti-ROBO1 CAR-293 cells were stained with 100 μL of 10 μg/mL of FITC-Labeled Human ROBO1, His Tag (Cat. No. RB1-HF2H7) and negative control protein respectively, FITC signals was used to evaluate the binding activity (QC tested).

RB1-H82E5-Cell-based assay
 ROBO1 FACS

2e5 of Anti-ROBO1 CAR-293 cells were stained with 100 μL of 3 μg/mL of Biotinylated Human ROBO1, His,Avitag (Cat. No. RB1-H82E5) and negative control protein respectively, washed and then followed by PE-SA and analyzed with FACS (Routinely tested).

RB1-H82E5-ELISA
 ROBO1 ELISA

Immobilized Anti-ROBO1 Antibody, Mouse IgG1 at 1 μg/mL (100 μL/well) can bind Biotinylated Human ROBO1, His,Avitag (Cat. No. RB1-H82E5) with a linear range of 2-31 ng/mL (QC tested).

RB1-H82E5-MALS-HPLC
ROBO1 MALS images

The purity of Biotinylated Human ROBO1, His,Avitag (Cat. No. RB1-H82E5) is more than 90% and the molecular weight of this protein is around 100-122 kDa verified by SEC-MALS.

Synonym Name

ROBO1/DUTT1

Background

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
BiCAR-NK/T cell therapy (Asclepius Technology Company Group (Suzhou) Co., Ltd) Phase 2 Clinical Asclepius Technology Company Group Neoplasms Details
ROBO1 CAR-NK cell therapy (Asclepius Technology Company Group (Suzhou) Co., Ltd.) Phase 2 Clinical Asclepius Technology Company Group Solid tumours; Pancreatic Neoplasms Details
BiCAR-NK/T cell therapy (Asclepius Technology Company Group (Suzhou) Co., Ltd) Phase 2 Clinical Asclepius Technology Company Group Neoplasms Details
ROBO1 CAR-NK cell therapy (Asclepius Technology Company Group (Suzhou) Co., Ltd.) Phase 2 Clinical Asclepius Technology Company Group Solid tumours; Pancreatic Neoplasms Details

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