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Your Position: Home > CCL5

CCL5

Brief Information

Name:C-C motif chemokine 5
Target Synonym:Beta-Chemokine RANTES,Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted,RANTES,TCP228,SIS-Delta,SISd,Small-Inducible Cytokine A5,D17S136E,T Cell-Specific Protein P228,EoCP,C-C Motif Chemokine 5,C-C Motif Chemokine Ligand 5,CCL5,Small Inducible Cytokine A5 (RANTES),Chemokine (C-C Motif) Ligand 5,T-Cell Specific RANTES Protein,T-Cell Specific Protein P288,Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5,Eosinophil Chemotactic Cytokine,T-Cell-Specific Protein RANTES,S
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CC5-H5251 Human Human CCL5/RANTES Protein, Fc Tag (MALS verified)
CC5-H5251-structure
CC5-H5251-sds
ACRO Quality

Part of Bioactivity data

CC5-H5251-MALS-HPLC
CCL5 MALS images

The purity of Human CCL5, Fc Tag (Cat. No. CC5-H5251) is more than 85% and the molecular weight of this protein is around 71-96 kDa verified by SEC-MALS.

CC5-H5251-ELISA
CCL5 ELISA

Immobilized Human CXCL4, His Tag (Cat. No. CX4-H52H9) at 5 μg/mL (100 μL/well) can bind Human CCL5, Fc Tag (Cat. No. CC5-H5251) with a linear range of 0.156-2.5 μg/mL (QC tested).

Protocol

Synonym Name

EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,D17S136E, SCYA5,CCL5,C-C motif chemokine 5T-cell-specific protein RANTES

Background

C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
AFX-5931 AFX-5931 Phase 2 Clinical Afecta Pharmaceuticals Eczema Details

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