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Your Position: Home > Galectin-1

Galectin-1

Brief Information

Name:Galectin-1
Target Synonym:Epididymis Secretory Sperm Binding Protein,Lectin, Galactoside-Binding, Soluble, 1,Beta-Galactoside-Binding Lectin L-14-I,14 KDa Laminin-Binding Protein,S-Lac Lectin 1,14 KDa Lectin,Galaptin,HLBP14,Gal-1,HPL,Beta-Galactoside-Binding Protein 14kDa,Lectin Galactoside-Binding Soluble 1,GAL1,GBP,Galectin 1,Putative MAPK-activating protein PM12,Galectin-1,HBL,LGALS1,Lactose-binding lectin 1
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
GA1-H4113 Human Human Galectin-1 / LGALS1 Protein, Tag Free (MALS verified)
GA1-H4113-structure
GA1-H4113-sds
ACRO Quality

Part of Bioactivity data

GA1-H4113-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human CD45, His,Avitag (Cat. No. CD5-H82E7) on SA Biosensor, can bind Human Galectin-1, Tag Free (Cat. No. GA1-H4113) with an affinity constant of 2.0 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Protocol
GA1-H4113-MALS-HPLC
Human Galectin-1, Tag Free (Cat. No. ) MALS images

The purity of Human Galectin-1, Tag Free (Cat. No. GA1-H4113) is more than 90% and the molecular weight of this protein is around 25-35 kDa verified by SEC-MALS.

Report
Bioactivity-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Biotinylated Human CD45, His,Avitag (Cat. No. CD5-H82E7) on SA Biosensor, can bind Human Galectin-1, Tag Free (Cat. No. GA1-H4113) with an affinity constant of 2.0 μM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

Customer Reviews

Synonym Name

LGALS1,GAL1,GBP,Galectin-1,DKFZp686E23103

Background

Galectin-1 (Gal-1), a member of the β-galactoside-binding animal lectin family, has a wide range of biological activities, which makes it an attractive target for medical applications. Gal-1 is ubiquitously but differentially expressed in normal and pathological animal tissues, and a variety of biological activities, including modulation of innate and adaptive immune responses, malignant progression of tumor cells, etc.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Ocriplasmin A-01016; THR-409 Approved Thrombogenics Jetrea, Jejetrea United States Vitreomacular Adhesion Thrombogenics Inc 2012-10-17 Vitreous Detachment; Arterial Occlusive Diseases; Disease Progression; Stroke; Retinal Diseases; Diabetic macular oedema; Uveitis; Vitreomacular Adhesion; Venous Thrombosis; Eye Diseases; Macular Degeneration; Diabetic Retinopathy; Retinal Vein Occlusion Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Olitigaltin GB-0139; TD-139 Phase 2 Clinical The University Of Edinburgh, Lund University Foundation Idiopathic Pulmonary Fibrosis; Coronavirus Disease 2019 (COVID-19) Details

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