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IDO1

Brief Information

Name:Indoleamine 2,3-dioxygenase
Target Synonym:Indoleamine-pyrrole 2,3-dioxygenase,IDO1,IDO-1,INDO,IDO,Indoleamine-Pyrrole 2,3 Dioxygenase,Indole 2,3-Dioxygenase,EC 1.13.11.52,Indoleamine-Pyrrole 2,3,-Dioxygenase,Indoleamine 2,3-Dioxygenase 1,Indolamine 2,3 Dioxygenase,EC:1.13.11.52
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:14
Lastest Research Phase:Phase 3 Clinical

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By Product Status:
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Cat. No. Species Product Description Structure Purity Feature
ID1-H5143 Human Human IDO1 Protein, His Tag (active enzyme, MALS verified)
ID1-H5143-structure
ID1-H5143-sds
ACRO Quality

Part of Bioactivity data

The purity of Human IDO1 Protein, His Tag (Cat. No. ID1-H5143) is more than 85% and the molecular weight of this protein is around 40-60 kDa verified by SEC-MALS.

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Epacadostat INCB-024360; 71596A9R13 (UNII code); INCB-24360 Phase 3 Clinical Incyte Corp Carcinoma, Squamous Cell; Sarcoma; Peritoneal Neoplasms; Thymus Neoplasms; Colorectal Neoplasms; Leukemia, B-Cell; Lymphoma; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Urogenital Neoplasms; Glioma; Urethral Neoplasms; Fallopian Tube Neoplasms; Lung Neoplasms; Carcinoma, Pancreatic Ductal; Thymoma; Esophageal adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Melanoma; Carcinoma, Hepatocellular; Adenocarcinoma; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Ovarian Neoplasms; Lymphoma, B-Cell; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Abdominal Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Neoplasms; Nasopharyngeal Neoplasms; Myelodysplastic Syndromes; Glioblastoma; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Nasopharyngeal Carcinoma; Prostatic Neoplasms Details
Puliginurad YL-90148 Phase 3 Clinical YL-Pharma Hyperuricemia; Gout Details
Linrodostat ONO-7701; BMS-986205 Phase 3 Clinical Bristol-Myers Squibb Company Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Neoplasms; Glioblastoma; Skin Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Mouth Neoplasms; Endometrial Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Laryngeal Diseases Details
IO-102 IO-102 Phase 2 Clinical Herlev Hospital, Merck Sharp & Dohme Corp, Io Biotech Aps Carcinoma, Squamous Cell; Mouth Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Indoximod 1-MT; D-1MT; NLG-001; NLG-8189; NSC-721782 Phase 2 Clinical Newlink Genetics Co Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Leukemia, Myeloid, Acute; Lung Neoplasms; Glioma; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Prostatic Neoplasms; Solid tumours; Breast Neoplasms; Central Nervous System Neoplasms; Glioblastoma; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Medulloblastoma; Ependymoma Details
RiMO-301 RiMO-301 Phase 2 Clinical The University Of Chicago Head and Neck Neoplasms; Neoplasms Details
SHR-9146 HTI-1090; SHR-9146 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours; Neoplasms Details
KHK-2455 KHK-2455 Phase 1 Clinical Kyowa Hakko Kirin Co Ltd Solid tumours; Carcinoma; Neoplasms; Carcinoma, Transitional Cell Details
LPM-3480226 LY-01013; LPM-3480226 Phase 1 Clinical Luye Pharma Group Ltd Solid tumours Details
DN-1406131 DN-131; DN-1406131 Phase 1 Clinical Jiangxi Qingfeng Pharmaceutical Industry Co Ltd, Shanghai De Novo Pharmatech Co Ltd Solid tumours; Melanoma; Carcinoma, Non-Small-Cell Lung Details
NLG802 NLG-802 Phase 1 Clinical Lankenau Institute For Medical Research Solid tumours Details
MK-7162 MK-7162 Phase 1 Clinical Merck Sharp & Dohme Corp Solid tumours Details
Navoximod NLG-919; RG-6078; GDC-0919 Phase 1 Clinical Lankenau Institute For Medical Research, Lumos Pharma Inc Solid tumours Details
Epacadostat INCB-024360; 71596A9R13 (UNII code); INCB-24360 Phase 3 Clinical Incyte Corp Carcinoma, Squamous Cell; Sarcoma; Peritoneal Neoplasms; Thymus Neoplasms; Colorectal Neoplasms; Leukemia, B-Cell; Lymphoma; Esophageal Squamous Cell Carcinoma; Endometrial Neoplasms; Urogenital Neoplasms; Glioma; Urethral Neoplasms; Fallopian Tube Neoplasms; Lung Neoplasms; Carcinoma, Pancreatic Ductal; Thymoma; Esophageal adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Melanoma; Carcinoma, Hepatocellular; Adenocarcinoma; Carcinoma, Transitional Cell; Head and Neck Neoplasms; Ovarian Neoplasms; Lymphoma, B-Cell; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Stomach Neoplasms; Esophageal Neoplasms; Abdominal Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Neoplasms; Nasopharyngeal Neoplasms; Myelodysplastic Syndromes; Glioblastoma; Carcinoma, Ovarian Epithelial; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Urinary Bladder Neoplasms; Nasopharyngeal Carcinoma; Prostatic Neoplasms Details
Puliginurad YL-90148 Phase 3 Clinical YL-Pharma Hyperuricemia; Gout Details
Linrodostat ONO-7701; BMS-986205 Phase 3 Clinical Bristol-Myers Squibb Company Solid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Small Cell Lung Carcinoma; Neoplasms; Glioblastoma; Skin Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Mouth Neoplasms; Endometrial Neoplasms; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Carcinoma, Hepatocellular; Laryngeal Diseases Details
IO-102 IO-102 Phase 2 Clinical Herlev Hospital, Merck Sharp & Dohme Corp, Io Biotech Aps Carcinoma, Squamous Cell; Mouth Neoplasms; Carcinoma, Non-Small-Cell Lung Details
Indoximod 1-MT; D-1MT; NLG-001; NLG-8189; NSC-721782 Phase 2 Clinical Newlink Genetics Co Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Leukemia, Myeloid, Acute; Lung Neoplasms; Glioma; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Prostatic Neoplasms; Solid tumours; Breast Neoplasms; Central Nervous System Neoplasms; Glioblastoma; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Medulloblastoma; Ependymoma Details
RiMO-301 RiMO-301 Phase 2 Clinical The University Of Chicago Head and Neck Neoplasms; Neoplasms Details
SHR-9146 HTI-1090; SHR-9146 Phase 1 Clinical Jiangsu Hengrui Medicine Co Ltd Solid tumours; Neoplasms Details
KHK-2455 KHK-2455 Phase 1 Clinical Kyowa Hakko Kirin Co Ltd Solid tumours; Carcinoma; Neoplasms; Carcinoma, Transitional Cell Details
LPM-3480226 LY-01013; LPM-3480226 Phase 1 Clinical Luye Pharma Group Ltd Solid tumours Details
DN-1406131 DN-131; DN-1406131 Phase 1 Clinical Jiangxi Qingfeng Pharmaceutical Industry Co Ltd, Shanghai De Novo Pharmatech Co Ltd Solid tumours; Melanoma; Carcinoma, Non-Small-Cell Lung Details
NLG802 NLG-802 Phase 1 Clinical Lankenau Institute For Medical Research Solid tumours Details
MK-7162 MK-7162 Phase 1 Clinical Merck Sharp & Dohme Corp Solid tumours Details
Navoximod NLG-919; RG-6078; GDC-0919 Phase 1 Clinical Lankenau Institute For Medical Research, Lumos Pharma Inc Solid tumours Details

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