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CNR1

Brief Information

Name:Cannabinoid CB1 receptor
Target Synonym:Cannabinoid Receptor 1 (Brain),CNR1,Cannabinoid Receptor 1,CANN6,CB-R,CNR,CB1,Central Cannabinoid Receptor,CB1K5,CB1A,CB1R,Receptor, Cannabinoid, CB1
Number of Launched Drugs:2
Number of Drugs in Clinical Trials:22
Lastest Research Phase:Approved

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Cat. No. Species Product Description Structure Purity Feature
CN1-H52P6 Human Human CNR1 Full Length Protein (VLP)
ACRO Quality

Part of Bioactivity data

CN1-H52P6-MALS-HPLC
 CNR1 ELISA

Immobilized Human CNR1 Full Length Protein-VLP (Cat. No. CN1-H52P6) at 5 μg/mL (100 μL/well) can bind Human Anti-CNR1,Human IgG4 | Human Kappa with a linear range of 1-31 ng/mL (QC tested).

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Cannabidiol/Dronabinol THC-5; delta-9-THC/CBD; MPL-001; MPL-005; GW-1000; KL16-012; BOL-DP-o-04; GW-1000-02; PPP-001; MGC-ODT Approved Gw Pharmaceuticals Sativex, Qixleef Canada Muscle Spasticity; Multiple Sclerosis; Neuralgia; Cancer Pain; Chronic Pain null 2005-04-01 Arthritis, Psoriatic; Phobia, Social; Urinary Bladder, Overactive; Tic Disorders; Reflex Sympathetic Dystrophy; Huntington Disease; Muscle Spasticity; Neuromyelitis Optica; Sciatica; Malnutrition; Acute Pain; Tourette Syndrome; Dementia; Neuralgia; Panic Disorder; Stress Disorders, Post-Traumatic; Hepatic Insufficiency; Osteoarthritis, Knee; Back Pain; Drug Resistant Epilepsy; Hidradenitis Suppurativa; Agoraphobia; Renal Insufficiency, Chronic; Social Behavior; Low Back Pain; Cerebral Palsy; Corticobasal degeneration; Depression; Peripheral Nervous System Diseases; Sleep Initiation and Maintenance Disorders; Pain; Anxiety; Spinal Cord Injuries; Cancer Pain; Chronic Pain; Marijuana Use; Spasm; Renal Insufficiency; Squamous Cell Carcinoma of Head and Neck; Marijuana Abuse; Depressive Disorder, Major; Migraine Disorders; Neoplasms; Arthritis, Rheumatoid; Diabetic Neuropathies; Anxiety Disorders; Kidney Diseases; Anorexia; Essential Tremor; Opioid-Related Disorders; Neck Pain; Sleep Wake Disorders; Multiple Scler Details
Cannabidiol GWP-42003-P; BOL-DP-o-05; GW-42003; BTX-1204; ZYN-002; PTL-101; CHI-902; APH-1501; AVCN-583601; GLA-015; BTX-1503; BTX-1801; BTX-1702; PBX-1308; ART-12.11; ART-1211; RAD-011; BRCX-014; RLS-103; LYT-310; RAD011; GWP-42003 Approved Gw Pharmaceuticals Plc Cannepil, Zygel, Epidiolex, Epidyolex United States Epilepsies, Myoclonic; Lennox Gastaut Syndrome null 2018-06-25 Migraine Disorders; Peripheral Nervous System Diseases; Tobacco Use Cessation; Facial Pain; Marijuana Smoking; Ovarian Neoplasms; Acne Vulgaris; Tobacco Smoking; Substance-Related Disorders; Sleep Initiation and Maintenance Disorders; HIV Infections; Anxiety; Seizures; Tuberous Sclerosis; Schizophrenia; Marijuana Abuse; Rett Syndrome; Fatty Liver; Autism Spectrum Disorder; Child Behavior Disorders; Chronic Pain; Pain; Alcoholic Intoxication; Inflammatory Bowel Diseases; Marijuana Use; Diabetes Mellitus, Type 2; Appetitive Behavior; Brain Injuries, Traumatic; Spinal Cord Injuries; Depression; Opioid-Related Disorders; Bipolar Disorder; Dyspepsia; Psychotic Disorders; Brain Diseases; Blepharospasm; Coronavirus Disease 2019 (COVID-19); Musculoskeletal Pain; Neoplasms; Hyperalgesia; Sleep Wake Disorders; Chronic Urticaria; Graft vs Host Disease; Sturge-Weber Syndrome; Arthritis, Rheumatoid; Hoarding Disorder; Diabetic Neuropathies; Pancreatic Neoplasms; Dysmenorrhea; Glioblastoma; Schizophrenia Spectrum and Other Details
Cannabidiol/Dronabinol THC-5; delta-9-THC/CBD; MPL-001; MPL-005; GW-1000; KL16-012; BOL-DP-o-04; GW-1000-02; PPP-001; MGC-ODT Approved Gw Pharmaceuticals Sativex, Qixleef Canada Muscle Spasticity; Multiple Sclerosis; Neuralgia; Cancer Pain; Chronic Pain null 2005-04-01 Arthritis, Psoriatic; Phobia, Social; Urinary Bladder, Overactive; Tic Disorders; Reflex Sympathetic Dystrophy; Huntington Disease; Muscle Spasticity; Neuromyelitis Optica; Sciatica; Malnutrition; Acute Pain; Tourette Syndrome; Dementia; Neuralgia; Panic Disorder; Stress Disorders, Post-Traumatic; Hepatic Insufficiency; Osteoarthritis, Knee; Back Pain; Drug Resistant Epilepsy; Hidradenitis Suppurativa; Agoraphobia; Renal Insufficiency, Chronic; Social Behavior; Low Back Pain; Cerebral Palsy; Corticobasal degeneration; Depression; Peripheral Nervous System Diseases; Sleep Initiation and Maintenance Disorders; Pain; Anxiety; Spinal Cord Injuries; Cancer Pain; Chronic Pain; Marijuana Use; Spasm; Renal Insufficiency; Squamous Cell Carcinoma of Head and Neck; Marijuana Abuse; Depressive Disorder, Major; Migraine Disorders; Neoplasms; Arthritis, Rheumatoid; Diabetic Neuropathies; Anxiety Disorders; Kidney Diseases; Anorexia; Essential Tremor; Opioid-Related Disorders; Neck Pain; Sleep Wake Disorders; Multiple Scler Details
Cannabidiol GWP-42003-P; BOL-DP-o-05; GW-42003; BTX-1204; ZYN-002; PTL-101; CHI-902; APH-1501; AVCN-583601; GLA-015; BTX-1503; BTX-1801; BTX-1702; PBX-1308; ART-12.11; ART-1211; RAD-011; BRCX-014; RLS-103; LYT-310; RAD011; GWP-42003 Approved Gw Pharmaceuticals Plc Cannepil, Zygel, Epidiolex, Epidyolex United States Epilepsies, Myoclonic; Lennox Gastaut Syndrome null 2018-06-25 Migraine Disorders; Peripheral Nervous System Diseases; Tobacco Use Cessation; Facial Pain; Marijuana Smoking; Ovarian Neoplasms; Acne Vulgaris; Tobacco Smoking; Substance-Related Disorders; Sleep Initiation and Maintenance Disorders; HIV Infections; Anxiety; Seizures; Tuberous Sclerosis; Schizophrenia; Marijuana Abuse; Rett Syndrome; Fatty Liver; Autism Spectrum Disorder; Child Behavior Disorders; Chronic Pain; Pain; Alcoholic Intoxication; Inflammatory Bowel Diseases; Marijuana Use; Diabetes Mellitus, Type 2; Appetitive Behavior; Brain Injuries, Traumatic; Spinal Cord Injuries; Depression; Opioid-Related Disorders; Bipolar Disorder; Dyspepsia; Psychotic Disorders; Brain Diseases; Blepharospasm; Coronavirus Disease 2019 (COVID-19); Musculoskeletal Pain; Neoplasms; Hyperalgesia; Sleep Wake Disorders; Chronic Urticaria; Graft vs Host Disease; Sturge-Weber Syndrome; Arthritis, Rheumatoid; Hoarding Disorder; Diabetic Neuropathies; Pancreatic Neoplasms; Dysmenorrhea; Glioblastoma; Schizophrenia Spectrum and Other Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Dronabinol(AXIM Biotechnologies) Phase 3 Clinical Axim Biotech Neoplasms; Child Nutrition Disorders; Vomiting; Nausea; Cachexia; Sarcopenia; Anorexia Nervosa Details
Adezunap AP-707 Phase 3 Clinical CannaXan GmbH Multiple Sclerosis; Accidental Injuries; Low Back Pain; Diabetes Mellitus; Peripheral Nerve Injuries; Diabetic peripheral neuropathy; Back Pain; Neuralgia; Somatoform Disorders; Stroke; Peripheral Nervous System Diseases; Brachial Plexus Neuropathies; Phantom Limb; Pain, Postoperative; Diabetic Neuropathies; Brain Injuries, Traumatic; Chronic Pain; Pain; Paraplegia Details
Dronabinol(Vertanical) VER-01 Phase 3 Clinical Vertanical GmbH Back Pain; Low Back Pain Details
V-24343 V-24343; ANEB-001 Phase 2 Clinical Vernalis Plc Poisoning; Obesity Details
11C-MePPEP 11C-MePPEP Phase 2 Clinical Eli Lilly And Company Substance-Related Disorders; Obesity Details
AX-1602 AX-1602 Phase 2 Clinical Axim Biotech Psoriasis; Dermatitis, Atopic; Vitiligo Details
Nimacimab RYI-018; RYI-028; JNJ-2463 Phase 2 Clinical Bird Rock Bio Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Renal Insufficiency, Chronic; Obesity; Diabetic Gastroparesis Details
ART-2713 NEO-1940; ART-2713; ART27.13; AZD-1940 Phase 2 Clinical Astrazeneca Plc, Neomed Inc, Pfizer Inc Weight Loss; Pain; Anorexia; Cachexia; Low Back Pain Details
Cannabidiol/hydroxychloroquine IHL-675A; IHL-675 Phase 2 Clinical Incannex Healthcare Ltd Arthritis, Rheumatoid; Respiratory Distress Syndrome, Adult Details
AEF-0217 AEF-0217 Phase 2 Clinical Aelis Farma Down Syndrome Details
Monlunabant MRI-1891; NN9440–INV-202; INV-202 Phase 2 Clinical Inversago Pharma Inc Metabolic Syndrome; Metabolic Diseases; Diabetic Nephropathies; Obesity Details
Cannabidiol/Palmitoylethanolamide THX-210; SCI–210 Phase 2 Clinical Therapix Biosciences Ltd Autism Spectrum Disorder; Diabetic Neuropathies Details
IGC-AD1 IGC-AD1 Phase 2 Clinical University Of South Florida Anxiety; Depression; Alzheimer Disease; Psychomotor Agitation; Memory Disorders Details
AEF-0117 AEF-0117 Phase 2 Clinical National Institute On Drug Abuse, Aelis Farma Marijuana Abuse Details
[11C]OMAR [11C]JHU-75528 Phase 1 Clinical Johns Hopkins University School Of Medicine Marijuana Abuse; Schizophrenia Details
ZYN-001 ZYN-001 Phase 1 Clinical Zynerba Pharmaceuticals Neuralgia; Fibromyalgia Details
Tetrahydrocannabivarin GWP-42004; THCV; O-4394; DELTA9-THCV; GW-42004 Phase 1 Clinical Gw Pharmaceuticals Plc Diabetes Mellitus, Type 2; Hyperglycemia; Metabolic Syndrome; Obesity, Morbid; Hypercholesterolemia; Dyslipidemias Details
Zevaquenabant MRI-1867; (S)-MRI-1867; INV-101 Phase 1 Clinical National Institutes Of Health Scleroderma, Systemic; Colitis, Ulcerative Details
IPI 201(Isosceles Pharmaceuticals Inc ) IPI-201 Phase 1 Clinical Pain, Postoperative Details
GFB-024 Phase 1 Clinical Takeda Pharma Kidney Diseases; Endocrine System Diseases; Diabetic Nephropathies; Diabetes Complications; Diabetes Mellitus Details
DBPR-211 Phase 1 Clinical National Health Research Institutes Diabetes Mellitus, Type 2 Details
MP-10X MP-10X Clinical Medipure Holdings Pain Details
C20T5 C20T5 Murdoch Childrens Research Institute Details
C12T12 C12T12 Murdoch Childrens Research Institute Details
Dronabinol(AXIM Biotechnologies) Phase 3 Clinical Axim Biotech Neoplasms; Child Nutrition Disorders; Vomiting; Nausea; Cachexia; Sarcopenia; Anorexia Nervosa Details
Adezunap AP-707 Phase 3 Clinical CannaXan GmbH Multiple Sclerosis; Accidental Injuries; Low Back Pain; Diabetes Mellitus; Peripheral Nerve Injuries; Diabetic peripheral neuropathy; Back Pain; Neuralgia; Somatoform Disorders; Stroke; Peripheral Nervous System Diseases; Brachial Plexus Neuropathies; Phantom Limb; Pain, Postoperative; Diabetic Neuropathies; Brain Injuries, Traumatic; Chronic Pain; Pain; Paraplegia Details
Dronabinol(Vertanical) VER-01 Phase 3 Clinical Vertanical GmbH Back Pain; Low Back Pain Details
V-24343 V-24343; ANEB-001 Phase 2 Clinical Vernalis Plc Poisoning; Obesity Details
11C-MePPEP 11C-MePPEP Phase 2 Clinical Eli Lilly And Company Substance-Related Disorders; Obesity Details
AX-1602 AX-1602 Phase 2 Clinical Axim Biotech Psoriasis; Dermatitis, Atopic; Vitiligo Details
Nimacimab RYI-018; RYI-028; JNJ-2463 Phase 2 Clinical Bird Rock Bio Inc Metabolic Dysfunction-Associated Steatotic Liver Disease; Renal Insufficiency, Chronic; Obesity; Diabetic Gastroparesis Details
ART-2713 NEO-1940; ART-2713; ART27.13; AZD-1940 Phase 2 Clinical Astrazeneca Plc, Neomed Inc, Pfizer Inc Weight Loss; Pain; Anorexia; Cachexia; Low Back Pain Details
Cannabidiol/hydroxychloroquine IHL-675A; IHL-675 Phase 2 Clinical Incannex Healthcare Ltd Arthritis, Rheumatoid; Respiratory Distress Syndrome, Adult Details
AEF-0217 AEF-0217 Phase 2 Clinical Aelis Farma Down Syndrome Details
Monlunabant MRI-1891; NN9440–INV-202; INV-202 Phase 2 Clinical Inversago Pharma Inc Metabolic Syndrome; Metabolic Diseases; Diabetic Nephropathies; Obesity Details
Cannabidiol/Palmitoylethanolamide THX-210; SCI–210 Phase 2 Clinical Therapix Biosciences Ltd Autism Spectrum Disorder; Diabetic Neuropathies Details
IGC-AD1 IGC-AD1 Phase 2 Clinical University Of South Florida Anxiety; Depression; Alzheimer Disease; Psychomotor Agitation; Memory Disorders Details
AEF-0117 AEF-0117 Phase 2 Clinical National Institute On Drug Abuse, Aelis Farma Marijuana Abuse Details
[11C]OMAR [11C]JHU-75528 Phase 1 Clinical Johns Hopkins University School Of Medicine Marijuana Abuse; Schizophrenia Details
ZYN-001 ZYN-001 Phase 1 Clinical Zynerba Pharmaceuticals Neuralgia; Fibromyalgia Details
Tetrahydrocannabivarin GWP-42004; THCV; O-4394; DELTA9-THCV; GW-42004 Phase 1 Clinical Gw Pharmaceuticals Plc Diabetes Mellitus, Type 2; Hyperglycemia; Metabolic Syndrome; Obesity, Morbid; Hypercholesterolemia; Dyslipidemias Details
Zevaquenabant MRI-1867; (S)-MRI-1867; INV-101 Phase 1 Clinical National Institutes Of Health Scleroderma, Systemic; Colitis, Ulcerative Details
IPI 201(Isosceles Pharmaceuticals Inc ) IPI-201 Phase 1 Clinical Pain, Postoperative Details
GFB-024 Phase 1 Clinical Takeda Pharma Kidney Diseases; Endocrine System Diseases; Diabetic Nephropathies; Diabetes Complications; Diabetes Mellitus Details
DBPR-211 Phase 1 Clinical National Health Research Institutes Diabetes Mellitus, Type 2 Details
MP-10X MP-10X Clinical Medipure Holdings Pain Details
C20T5 C20T5 Murdoch Childrens Research Institute Details
C12T12 C12T12 Murdoch Childrens Research Institute Details

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