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Your Position: Home > NT-4

NT-4

Brief Information

Name:5-nucleotidase
Target Synonym:5 Nucleotidase (CD73),5 -nucleotidase,5 -Nucleotidase, Ecto (CD73),Ecto-5 -nucleotidase,NT5E,5 -Nucleotidase Ecto,Ecto-5-Nucleotidase,5-NT,Purine 5-Prime-Nucleotidase,5-Nucleotidase, Ecto (CD73),5 Nucleotidase (CD73),5-Nucleotidase Ecto,5-Nucleotidase,CD73 Antigen,EC 3.1.3.5,CALJA,E5NT,ENT,NT,EN,CD73,5 -NT,NT5,NTE,EC:3.1.3.5
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:29
Lastest Research Phase:Phase 3 Clinical

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Cat. No. Species Product Description Structure Purity Feature
NT4-H5114 Human Human NT-4 / Neurotrophin-4 Protein, Tag Free, low endotoxin (MALS verified)
NT4-H5114-structure
NT4-H5114-sds
ACRO Quality

Part of Bioactivity data

NT4-H5114-MALS-HPLC
NT-4 MALS images

The purity of Human NT-4, Tag Free (Cat. No. NT4-H5114) is more than 95% and the molecular weight of this protein is around 32-40 kDa verified by SEC-MALS.

NT4-H5114-ELISA
NT-4 ELISA

Immobilized Human NT-4, Tag Free (Cat. No. NT4-H5114) at 5 μg/mL (100 μL/well) can bind Human TrkB, Fc Tag (Cat. No. NT2-H5254) with a linear range of 2-10 ng/mL (QC tested).

Protocol

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Uliledlimab TJ-4309; TJ-004309; TJD-5 Phase 3 Clinical I-Mab Biopharma Co Ltd Solid tumours; Ovarian Neoplasms; Head and Neck Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Neoplasm Metastasis Details
Oleclumab MEDI-9447 Phase 3 Clinical Medimmune Llc Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma; Hemangiosarcoma; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Liposarcoma; Prostatic Neoplasms; Osteosarcoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
Dalutrafusp alfa GS-1423; AGEN-1423 Phase 2 Clinical Agenus Inc Liver Neoplasms; Solid tumours; Pancreatic Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal Details
Interferon beta-1a (Faron Pharmaceuticals) MR-11A8; FP-1201; FP-1201-lyo Phase 2 Clinical Faron Pharmaceuticals Ltd Multiple Organ Failure; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Mantle-Cell; Leukemia, B-Cell; Lymphoma, Non-Hodgkin; Acute Lung Injury Details
BMS-986179 BMS-986179 Phase 2 Clinical Bristol-Myers Squibb Company Solid tumours Details
Mupadolimab CPX-006; COR-004 (Corvus Pharmaceuticals); CPI-006 Phase 2 Clinical Corvus Pharmaceuticals Inc Papillomavirus Infections; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Lymphoma, Non-Hodgkin; Endometrial Neoplasms; Colorectal Neoplasms; Sarcoma; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Solid tumours; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Coronavirus Disease 2019 (COVID-19); Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Head and Neck Neoplasms; Ovarian Neoplasms Details
Quemliclustat AB-680 Phase 2 Clinical Arcus Biosciences Inc Biliary Tract Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Cholangiocarcinoma; Prostatic Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
Dresbuxelimab AK-119 Phase 2 Clinical Akeso Pharmaceuticals Inc Solid tumours; Coronavirus Disease 2019 (COVID-19); Idiopathic Pulmonary Fibrosis; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
S-095024 S-095024; S095024 Phase 2 Clinical Institut De Recherches Internationales Servier, Servier Bio-Innovation LLC Carcinoma, Non-Small-Cell Lung Details
HB-0045 HB-0045; HB0045 Phase 2 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Solid tumours Details
JAB-BX102 JAB-BX102 Phase 2 Clinical Jacobio Pharmaceuticals Co Ltd Solid tumours Details
LY-3475070 LY-3475070 Phase 1 Clinical Eli Lilly And Company Neoplasms Details
Anti-CD73 monoclonal antibody (Bristol-Myers Squibb) Phase 1 Clinical Bristol-Myers Squibb Company Neoplasms Details
Uprevstobart INCA-00186 Phase 1 Clinical Incyte Corp Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Gastrointestinal Neoplasms Details
HB-0052 HB-0052; HB0052 Phase 1 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Solid tumours Details
BPI-472372 BPI-472372 Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours Details
BB-1709 BB-1709 Phase 1 Clinical Bliss Biopharmaceutical (Hangzhou) Co Ltd Solid tumours Details
PM-1015 PM1015; PM-1015 Phase 1 Clinical Biotheus Inc Solid tumours Details
AK-131 AK-131 Phase 1 Clinical Zhongshan Akeso Biopharma Co Ltd Solid tumours; Neoplasms Details
PT-199 PT-199 Phase 1 Clinical Phanes Therapeutics Inc Solid tumours; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
IBI-325 IBI-325 Phase 1 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours Details
BR-101 BR101; BR-101 Phase 1 Clinical BioRay Pharmaceutical Co Ltd Solid tumours Details
CB-708 CB-708; CB708; ATG-037 Phase 1 Clinical Calithera Biosciences Inc Solid tumours; Neoplasms Details
HLX-23 HLX-23 Phase 1 Clinical Shanghai Henlius Biologics Co Ltd Solid tumours; Lymphoma Details
ORIC533 ORIC-533 Phase 1 Clinical Oric Pharmaceuticals Inc Multiple Myeloma; Neoplasm Metastasis Details
IPH-5301 IPH-5301 Phase 1 Clinical Innate Pharma Ovarian Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms; Endometrial Neoplasms; Neoplasm Metastasis Details
HBM-1007 HBM1007; R 1007; HBM 1007; HBM-1007 Phase 1 Clinical Harbour Biomed Solid tumours; Neoplasms Details
ABSK-051 ABSK051 Phase 1 Clinical ABbisko Therapeutics Co Ltd Solid tumours; Neoplasms Details
Uliledlimab TJ-4309; TJ-004309; TJD-5 Phase 3 Clinical I-Mab Biopharma Co Ltd Solid tumours; Ovarian Neoplasms; Head and Neck Neoplasms; Triple Negative Breast Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Non-Small-Cell Lung; Gastrointestinal Neoplasms; Neoplasm Metastasis Details
Oleclumab MEDI-9447 Phase 3 Clinical Medimmune Llc Solid tumours; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Carcinoma; Hemangiosarcoma; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Prostatic Neoplasms, Castration-Resistant; Liposarcoma; Prostatic Neoplasms; Osteosarcoma; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma Details
Dalutrafusp alfa GS-1423; AGEN-1423 Phase 2 Clinical Agenus Inc Liver Neoplasms; Solid tumours; Pancreatic Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal Details
Interferon beta-1a (Faron Pharmaceuticals) MR-11A8; FP-1201; FP-1201-lyo Phase 2 Clinical Faron Pharmaceuticals Ltd Multiple Organ Failure; Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Mantle-Cell; Leukemia, B-Cell; Lymphoma, Non-Hodgkin; Acute Lung Injury Details
BMS-986179 BMS-986179 Phase 2 Clinical Bristol-Myers Squibb Company Solid tumours Details
Mupadolimab CPX-006; COR-004 (Corvus Pharmaceuticals); CPI-006 Phase 2 Clinical Corvus Pharmaceuticals Inc Papillomavirus Infections; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Lymphoma, Non-Hodgkin; Endometrial Neoplasms; Colorectal Neoplasms; Sarcoma; Prostatic Neoplasms, Castration-Resistant; Urinary Bladder Neoplasms; Solid tumours; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Coronavirus Disease 2019 (COVID-19); Squamous Cell Carcinoma of Head and Neck; Carcinoma, Renal Cell; Head and Neck Neoplasms; Ovarian Neoplasms Details
Quemliclustat AB-680 Phase 2 Clinical Arcus Biosciences Inc Biliary Tract Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Cholangiocarcinoma; Prostatic Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung Details
Dresbuxelimab AK-119 Phase 2 Clinical Akeso Pharmaceuticals Inc Solid tumours; Coronavirus Disease 2019 (COVID-19); Idiopathic Pulmonary Fibrosis; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung Details
S-095024 S-095024; S095024 Phase 2 Clinical Institut De Recherches Internationales Servier, Servier Bio-Innovation LLC Carcinoma, Non-Small-Cell Lung Details
HB-0045 HB-0045; HB0045 Phase 2 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Solid tumours Details
JAB-BX102 JAB-BX102 Phase 2 Clinical Jacobio Pharmaceuticals Co Ltd Solid tumours Details
LY-3475070 LY-3475070 Phase 1 Clinical Eli Lilly And Company Neoplasms Details
Anti-CD73 monoclonal antibody (Bristol-Myers Squibb) Phase 1 Clinical Bristol-Myers Squibb Company Neoplasms Details
Uprevstobart INCA-00186 Phase 1 Clinical Incyte Corp Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Gastrointestinal Neoplasms Details
HB-0052 HB-0052; HB0052 Phase 1 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Solid tumours Details
BPI-472372 BPI-472372 Phase 1 Clinical Betta Pharmaceuticals Co Ltd Solid tumours Details
BB-1709 BB-1709 Phase 1 Clinical Bliss Biopharmaceutical (Hangzhou) Co Ltd Solid tumours Details
PM-1015 PM1015; PM-1015 Phase 1 Clinical Biotheus Inc Solid tumours Details
AK-131 AK-131 Phase 1 Clinical Zhongshan Akeso Biopharma Co Ltd Solid tumours; Neoplasms Details
PT-199 PT-199 Phase 1 Clinical Phanes Therapeutics Inc Solid tumours; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung Details
IBI-325 IBI-325 Phase 1 Clinical Innovent Biologics(Suzhou) Co Ltd Solid tumours Details
BR-101 BR101; BR-101 Phase 1 Clinical BioRay Pharmaceutical Co Ltd Solid tumours Details
CB-708 CB-708; CB708; ATG-037 Phase 1 Clinical Calithera Biosciences Inc Solid tumours; Neoplasms Details
HLX-23 HLX-23 Phase 1 Clinical Shanghai Henlius Biologics Co Ltd Solid tumours; Lymphoma Details
ORIC533 ORIC-533 Phase 1 Clinical Oric Pharmaceuticals Inc Multiple Myeloma; Neoplasm Metastasis Details
IPH-5301 IPH-5301 Phase 1 Clinical Innate Pharma Ovarian Neoplasms; Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Neoplasms; Breast Neoplasms; Lung Neoplasms; Endometrial Neoplasms; Neoplasm Metastasis Details
HBM-1007 HBM1007; R 1007; HBM 1007; HBM-1007 Phase 1 Clinical Harbour Biomed Solid tumours; Neoplasms Details
ABSK-051 ABSK051 Phase 1 Clinical ABbisko Therapeutics Co Ltd Solid tumours; Neoplasms Details

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