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Your Position: Home > Clusterin

Clusterin

Brief Information

Name:Clusterin
Target Synonym:Epididymis Secretory Sperm Binding Protein,CLI,Apolipoprotein J,ApoJbeta,Complement cytolysis inhibitor a chain,Testosterone-repressed prostate message 2,Complement cytolysis inhibitor b chain,ApoJalpha,AAG4,Complement cytolysis inhibitor,NA1/NA2,APOJ,CLU,Clusterin,Complement-Associated Protein SP-40,40,Complement Lysis Inhibitor,Sulfated Glycoprotein 2,Ku70-Binding Protein 1,TRPM-2,KUB1,Clusterin (Complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Mes
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Cat. No. Species Product Description Structure Purity Feature
CLU-H5227 Human Human Clusterin / CLUS Protein, His Tag
CLU-H5227-structure
CLU-H5227-sds
ACRO Quality

Part of Bioactivity data

CLU-H5227-MALS-HPLC
Clusterin SPR

Human Clusterin, His Tag (Cat. No. CLU-H5227) immobilized on CM5 Chip can bind Human VLDL R, His Tag (Cat. No. VLR-H5227 ) with an affinity constant of 265 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Protocol

Synonym Name

CLU,Clusterin,AAG4,APOJ,CLI,KUB1,SGP-2,SP-40,TRPM2

Background

Clusterin (CLU) is also known as dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI), is a secreted multifunctional glycoprotein protein which belongs to the clusterin family. Intracellular cleavages of the precursor of clusterin remove the signal peptide and generate comparably sized ¦Á and ¦Â chains which are secreted as an 80 kDa N

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Sotevtamab AB-sCLU mAB; 16B5; AB-16B5 Phase 2 Clinical National Research Council Biotechnology Research Institute Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis Details

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