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Your Position: Home > Chitotriosidase

Chitotriosidase

Brief Information

Name:Chitinase 1
Target Synonym:EC:3.2.1.14,Chitotriosidase-1,CHIT,Chitinase-1,CHIT1,Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase,CHI3,CHITD,EC 3.2.1.14,Chitinase 1 (Chitotriosidase),Chitinase 1,Chitotriosidase
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Synonym Name

Chitotriosidase-1,Chitinase-1,CHIT1,Chitinase1,CHI3

Background

Chitotriosidase-1 (CHIT1), a member of the glycosyl hydrolase 18 family and Chitinase class II subfamily, is also known as Chitinase-1, which contains one chitin-binding type-2 domain. As the digestive enzymes, Chitinases can break down glycosidic bonds in chitin. The chitin-binding type-2 domain of CHIT1 is able to degrade chitin and chitotriose. Chitin, like cellulose, has been thought of as abundant but difficult to digest. Furthermore, CHIT1 may participate in the defense against nematodes and other pathogens.

Clinical and Translational Updates

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