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Your Position: Home > MMP-8

MMP-8

Brief Information

Name:Matrix metalloproteinase 8
Target Synonym:EC 3.4.24,Matrix metalloproteinase-8,MMP-8,MMP8,Matrix Metallopeptidase 8,Matrix Metalloproteinase 8 (Neutrophil Collagenase),PMNL-CL,CLG1,PMN Leukocyte Collagenase,Neutrophil Collagenase,EC 3.4.24.34,HNC,Matrix Metalloproteinase 8,EC:3.4.24.34,PMNL Collagenase,Collagenase 2
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Discontinued

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Cat. No. Species Product Description Structure Purity Feature
MM8-M52H7 Mouse Mouse MMP-8 Protein, His Tag (active enzyme, MALS verified)
MM8-M52H7-structure
MM8-M52H7-sds
MM8-H52H7 Human Human MMP-8 Protein, His Tag (active enzyme)
MM8-H52H7-structure
MM8-H52H7-sds
ACRO Quality

Part of Bioactivity data

MM8-M52H7-MALS-HPLC
MMP-8 MALS images

The purity of Mouse MMP-8 Protein, His Tag (Cat. No. MM8-M52H7) is more than 90% and the molecular weight of this protein is around 28-40 kDa verified by SEC-MALS.

MM8-H52H7-ELISA
MMP-8 ELISA

Immobilized Human MMP-8 Protein, His Tag (Cat. No. MM8-H52H7) at 1 μg/mL (100 μL/well) can bind various dilution ratio of Anti-MMP8 Polyclonal Antibody (Routinely tested).

Protocol

Synonym Name

CLG1 Protein, HNC Protein, MMP-8 Protein,  PMNL-CL Protein,

Background

Matrix metalloproteinase-8（MMP-8）also known as neutrophil collagenase and CLG1, is a member of matrix metalloproteinases (MMPs) family, which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis.

Clinical and Translational Updates

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