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KIR3DL3

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Cat. No. Species Product Description Structure Purity Feature
KI3-H82F3 Human Biotinylated Human KIR3DL3 / CD158z Protein, Fc,Avitag™
KI3-H82F3-structure
KI3-H82F3-sds
KI3-H5259 Human Human KIR3DL3 / CD158z Protein, Fc Tag
KI3-H5259-structure
KI3-H5259-sds
ACRO Quality

Part of Bioactivity data

KI3-H82F3-MALS-HPLC
 KIR3DL3 ELISA

Immobilized Biotinylated Human KIR3DL3 / CD158z Protein, Fc,Avitag (Cat. No. KI3-H82F3) at 2 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human B7-H7, His Tag (Cat. No. B77-H52H6) with a linear range of 0.02-5 μg/mL (QC tested).

Synonym Name

Killer cell immunoglobulin-like receptor 3DL3,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1,CD158z,KIR3DL3,KIR3DL7,KIRC1

Background

the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with120 distinct polymorphic alleles of the coding sequence [

Clinical and Translational Updates

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