Acrobiosystems for English
icon_bulk_orderBulk inquiry/Quick order
user
  1. Dashboard
  2. My Profile
  3. My Address
  4. My Orders
  5. Acro Membership
Login Register
Promotion
Recombinant Proteins ClearClear history
Recombinant Proteins CloseClose
Browse Products By Molecule Name a-zA-Z
TL1A Hot |GMP Cytokines Hot |FcRn Binding Kit (TR-FRET) New |Claudin 18.2
0
There is no goods in the shopping cart !
My Cart|Secure Checkout
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > Siglec-7

Siglec-7

Brief Information

Name:Sialic acid-binding Ig-like lectin 7
Target Synonym:CDw328,AIRM-1,Adhesion inhibitory receptor molecule 1,D-siglec,QA79 membrane protein,CD328
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:

Product ListCompare or Buy

Product> Filter Results
By Product Status:
By Product Category:
By Species:
By Tag:
By Conjugate:
Cat. No. Species Product Description Structure Purity Feature
SI7-H5258 Human Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag (MALS verified)
SI7-H5258-structure
SI7-H5258-sds
SI7-H5257 Human Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag (MALS verified)
SI7-H5257-structure
SI7-H5257-sds
SG7-H82E7 Human Biotinylated Human Siglec-7 / CD328 Protein, His,Avitag™ (MALS & SPR verified)
SG7-H82E7-structure
SG7-H82E7-sds
SG7-H5225 Human Human Siglec-7 / CD328 Protein, His Tag (MALS verified)
SG7-H5225-structure
SG7-H5225-sds
ACRO Quality

Part of Bioactivity data

SG7-H82E7-SPR
Human_FcRn_Heterodimer_Protein_SPR

Biotinylated Human Siglec-7, His,Avitag (Cat. No. SG7-H82E7) immobilized on CM5 Chip can bind Neu5Aca2-6GalNAca-PAA-biotin with an affinity constant of 29.2 nM as determined in a SPR assay (Biacore 8K) (QC tested).

Protocol
SI7-H5257-ELISA
Siglec-7 ELISA

Immobilized Human Siglec-7, Fc (L118A, G120A, E201A) Tag (Cat. No. SI7-H5257) at 5 μg/mL (100 μL/well) can bind Neu5Aca2-6GalNAca-PAA-biotin with a linear range of 0.02-0.313 ng/mL (QC tested).

Protocol

Synonym Name

CDw328, D-siglec, A79 membrane protein, p75,Adhesion inhibitory receptor molecule 1, AIRM-1

Background

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Clinical and Translational Updates

    This web search service is supported by Google Inc.

    totop
    Call us
    Call us
    North America:
    +1 800-810-0816 (Toll Free)
    Asia & Pacific:
    +86 400-682-2521
    Email
    Email
    order@acrobiosystems.com
    Fax
    Fax
    +1 888-377-6111
    Address
    Address
    1 Innovation Way, Newark, DE 19711, USA
    linkedin twitter facebook youtube

    Leave a message

    Copyright © 2017 ACROBiosystems. All Rights Reserved
    |Related Links|Privacy Policy|Terms and Conditions|Legal|Sitemap