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Your Position: Home > Protein > Cardiotrophin 1 > CA1-H5243

Human Cardiotrophin 1 Protein, His Tag (MALS verified)

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  • Synonym
    CT-1, CT1
  • Source
    Human Cardiotrophin 1 Protein, His Tag(CA1-H5243) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Ala 201 (Accession # Q16619-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Cardiotrophin 1 Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 23 kDa. The protein migrates as 27-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM HAC, pH3.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Cardiotrophin 1 SDS-PAGE

Human Cardiotrophin 1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

SEC-MALS
Cardiotrophin 1 MALS images

The purity of Human Cardiotrophin 1 Protein, His Tag (Cat. No. CA1-H5243) is more than 90% and the molecular weight of this protein is around 25-35 kDa verified by SEC-MALS.

  • Background
    The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene.
  • Clinical and Translational Updates

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