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Your Position: Home > Antibody > PEG > PEG-M731

Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6)

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  • Source
    Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human IgG1 constant domain.

  • Host Species
    Human
  • Isotype
    Human IgG1 | Human Kappa
  • Specificity
    This product is a specific antibody specifically reacts with PEG.
  • Antibody Type

    Human-Mouse Chimeric Monoclonal

  • Purity

    >95% as determined by SDS-PAGE.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Conjugate

    Unconjugated

  • Purification

    Protein A purified/ Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in HAC, pH3.0 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
PEG SDS-PAGE

Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

Bioactivity-Elisa
 PEG ELISA

Immobilized PEG Coated Plates, Clear, 12×8-Well Strips, White Frame at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-PEG Antibody, Human IgG1 (5G3-1C6) (Cat. No. PEG-M731) with a linear range of 0.004-0.125 μg/mL (QC tested).

  • Background
    Polyethylene glycol, referred to as PEG, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments, and suppository base, and tablet and capsule lubricant. PEG has low toxicity with systemic absorption less than 0.5%.
    PEGylation occurs when PEGs are attached to various protein medications, allowing for greater solubility for certain drugs. Examples of PEGylated medications include PEG-interferon alpha (Pegintron) and PEG-filgrastim (Neulasta).
  • Clinical and Translational Updates

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