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TROP-2

TROP-2 Overview

English NameTumor-associated calcium signal transducer 2Approved Drugs3
Drugs in Clinical Trials27Target SynonymTumor-associated calcium signal transducer 2，M1S1，TROP2，TACSTD2，Pancreatic carcinoma marker protein GA733-1，Tumor Associated Calcium Signal Transducer 2，GA733-1，Membrane Component， Chromosome 1， Surface Marker 1，Gastrointestinal Tumor-Associated Antigen GA7331，Pancreatic Carcinoma Marker Protein GA7331，Cell surface glycoprotein Trop-2，Membrane component chromosome 1 surface marker 1，40kD Glycoprotein， Identified By Monoclonal Antibody GA733，Cell Surface Glycoprotein TROP2，Epithelial Glycoprotein-1，Truncated TACSTD2，GA7331，EGP-1，EGP1，GP50，Trophoblast Cell Surface Antigen 2
Highest Development StageApproved
English NameTumor-associated calcium signal transducer 2
Target SynonymTumor-associated calcium signal transducer 2，M1S1，TROP2，TACSTD2，Pancreatic carcinoma marker protein GA733-1，Tumor Associated Calcium Signal Transducer 2，GA733-1，Membrane Component， Chromosome 1， Surface Marker 1，Gastrointestinal Tumor-Associated Antigen GA7331，Pancreatic Carcinoma Marker Protein GA7331，Cell surface glycoprotein Trop-2，Membrane component chromosome 1 surface marker 1，40kD Glycoprotein， Identified By Monoclonal Antibody GA733，Cell Surface Glycoprotein TROP2，Epithelial Glycoprotein-1，Truncated TACSTD2，GA7331，EGP-1，EGP1，GP50，Trophoblast Cell Surface Antigen 2
Approved Drugs3
Drugs in Clinical Trials27
Highest Development StageApproved

TROP-2 Product List

  • Product Category

    Protein (18)Beads (1)Antibody (1)Kits (1)

  • Product Status

    Launched (22)

  • Species

    Human (9)Mouse (4)Rhesus macaque (4)Canine (1)Rabbit (1)Cynomolgus (2)

  • Tag

    His Tag (8)His Tag & Avi Tag (5)Fc Tag (2)- (4)Fc Tag & Avi Tag (3)

  • Conjugate

    Unconjugated (11)Biotin-labeled (8)- (3)

Total: 21
  • 1
  • 2
  • 3

TROP-2 Background

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

TROP-2 Synonyms

TACSTD2,GA733-1,M1S1,TROP2

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Product Reviews

  • M***g2023-07-06
    0People Like
    Human TROP-2 / TACSTD2 Protein, Fc Tag (MALS verified)
    This protein was used to immunize mice for antibody development. Proteins were mixed with CFA/IFA and immunized intraperitoneally. Mice were boosted every 14 days for 5 boosts following initial immunization. Serum titers were measured by ELISA following Days 0, 43, and 65. Of the two mice immunized with this protein, only one mouse developed an antibody response as low signal was detected at day 65.
  • V***w2023-02-21
    2People Like
    Human TROP-2 / TACSTD2 Protein, His Tag, low endotoxin (MALS verified)
    Acro and their customer support are super helpful. Products ordered arrived in a timely manner. Customer support personal are as friendly as they are insightful. Never have they disappointed when purchasing any of their products. Such a user friendly website and if anything is not found customer support never backs down to help out! Acro’s personal are very friendly and knowledgeable. They were friendly and helpful when resolving this issue.
  • E***l2022-10-26
    1People Like
    Human TROP-2 / TACSTD2 Protein, His Tag, low endotoxin (MALS verified)
    Acro’s customer support is always super helpful and quick to respond. When products are ordered, the arrive in a timely manner. Acro’s personal are very friendly and knowledgeable. They never disappoint when it comes to finding a solution to a problem. Having such a user-friendly website helps a lot in finding the right product needed and if something cannot be found customer support always finds a way!
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