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TPBG

TPBG Overview

English NameTrophoblast glycoproteinApproved Drugs0
Drugs in Clinical Trials15Target SynonymTrophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG
Highest Development StagePhase 2 Clinical
English NameTrophoblast glycoprotein
Target SynonymTrophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG
Approved Drugs0
Drugs in Clinical Trials15
Highest Development StagePhase 2 Clinical

TPBG Product List

  • Product Category

    Protein (8)Cell (1)

  • Product Status

    Launched (10)

  • Species

    Human (5)Cynomolgus / Rhesus macaque (1)Mouse (2)Rat (1)

  • Tag

    His Tag & Avi Tag (2)Fc Tag (2)His Tag (3)Fc Tag & Avi Tag (1)- (2)

  • Conjugate

    Biotin-labeled (2)Unconjugated (6)- (2)

Total: 9
  • 1

TPBG Background

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

TPBG Synonyms

TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

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