Select Language
Free Registration

PVRIG

PVRIG Overview

English NameTransmembrane protein PVRIGApproved Drugs0
Drugs in Clinical Trials7Target SynonymPVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463
Highest Development StagePhase 2 Clinical
English NameTransmembrane protein PVRIG
Target SynonymPVRIG，PVR Related Immunoglobulin Domain Containing，CD112 Receptor，Poliovirus Receptor-Related Immunoglobulin Domain-Containing Protein，Poliovirus Receptor Related Immunoglobulin Domain Containing，Nectin-2 Receptor，C7orf15，CD112R，Transmembrane Protein PVRIG，MGC2463
Approved Drugs0
Drugs in Clinical Trials7
Highest Development StagePhase 2 Clinical

PVRIG Product List

  • Product Category

    Protein (11)

  • Product Status

    Launched (12)

  • Species

    Human (5)Mouse (4)Cynomolgus (2)

  • Tag

    His Tag (4)Fc Tag (3)His Tag & Avi Tag (2)Mouse IgG Fc Tag (1)Fc Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (8)Biotin-labeled (3)

Total: 11
  • 1
  • 2

PVRIG Background

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

PVRIG Synonyms

C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor

Antibody Project Trading Platform

  • Overview
  • Product List