PTK7

PTK7 Overview

English NameProtein-tyrosine kinase 7Approved Drugs0
Drugs in Clinical Trials5Target SynonymColon carcinoma kinase 4,Inactive tyrosine-protein kinase 7,Tyrosine-protein kinase-like 7,CCK-4,PTK7,Protein Tyrosine Kinase 7 (Inactive),Pseudo Tyrosine Kinase Receptor 7,PTK7 Protein Tyrosine Kinase 7,CCK4,Protein-Tyrosine Kinase 7,Protein Tyrosine Kinase 7
Highest Development StagePhase 2 Clinical
English NameProtein-tyrosine kinase 7
Target SynonymColon carcinoma kinase 4,Inactive tyrosine-protein kinase 7,Tyrosine-protein kinase-like 7,CCK-4,PTK7,Protein Tyrosine Kinase 7 (Inactive),Pseudo Tyrosine Kinase Receptor 7,PTK7 Protein Tyrosine Kinase 7,CCK4,Protein-Tyrosine Kinase 7,Protein Tyrosine Kinase 7
Approved Drugs0
Drugs in Clinical Trials5
Highest Development StagePhase 2 Clinical

PTK7 Product List

  • Product Category

    Protein (10)Cell (1)

  • Product Status

    Launched (11)

  • Species

    Human (5)Mouse (2)Rabbit (1)Cynomolgus / Rhesus macaque (1)Rat (2)

  • Tag

    His Tag (5)His Tag & Avi Tag (1)Fc Tag (3)Fc Tag & Avi Tag (1)- (1)

  • Conjugate

    Unconjugated (8)Biotin-labeled (2)- (1)

Total: 11
  • 1
  • 2

PTK7 Background

PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

PTK7 Synonyms

PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7

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