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Protein L

Protein L Product List

  • Product Category

    Protein (3)Beads (1)Kits (1)

  • Product Status

    Launched (5)

  • Species

    Peptostreptococcus magnus (4)- (1)

  • Tag

    His Tag (2)His Tag & Avi Tag (1)- (2)

  • Conjugate

    Unconjugated (1)Biotin-labeled (1)PE Labeled (1)- (2)

Total: 5
  • 1

Protein L Background

Protein L was isolated from the surface of bacterial species Peptostreptococcus magnus and was found to bind Ig(IgG,IgM,IgA,IgE and IgD) through L chain interaction, from which the name was suggested. Despite this wide-ranging binding capability with respect to Ig classes, Protein L is not a universal immunoglobilin-binding protein. Binding of Protein L to immunoglobulins is restricted to those containing kappa light chains (i.e., k chain of the VL domain). In humans and mice, kappa (k) light chains predominate. The remaining immunoglobulins have lambda (l) light chains. The recombinant protein contains four immunoglobulin (Ig) binding domains (Bdomains) of the native protein. Besides antibody, protein L is also suitable for binding of a wide range of antibody fragments such as Fabs, single-chain variable fragments (scFv), and domain antibodies (Dabs).

Product Reviews

  • 1***02022-08-03
    1People Like
    PE-Labeled Recombinant Protein L, His Tag (Site-specific conjugation)
    The pl antibody can detect the scfv region of most antigen CARs. We use it to detect the scfv of CD33 in our CD33 CAR-NK, and it can also be diluted with good results!
  • M***D2021-09-15
    1People Like
    Recombinant Protein L, His Tag
    I used recombinant protein L from ACROS Biosystems to prepare gold conjugates for immunosensors and rapid quantification of human IgG and was able to detect 2.5 ng of Human IgG in less than 1 minute. I highly recommend this product for the detection and isolation of antibodies and Fab'2 fragments. I will definitely be ordering this item again.
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