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PD-L2

PD-L2 Overview

English NameProgrammed death-ligand 2Approved Drugs0
Drugs in Clinical Trials3Target SynonymPDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
Highest Development StagePhase 2 Clinical
English NameProgrammed death-ligand 2
Target SynonymPDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
Approved Drugs0
Drugs in Clinical Trials3
Highest Development StagePhase 2 Clinical

PD-L2 Product List

  • Product Category

    Protein (8)

  • Product Status

    Launched (8)

  • Species

    Human (5)Mouse (3)

  • Tag

    His Tag (2)Fc Tag (2)Mouse IgG Fc Tag (1)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (5)Biotin-labeled (3)

Total: 8
  • 1

PD-L2 Background

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2 Synonyms

PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2

Product Reviews

  • 1***32019-10-11
    0People Like
    Human PD-L2 / B7-DC Protein, His Tag (SPR verified)
    ACROBiosystem's proteins have high purity. They totally meet our requirements. Most importantly, repeatability among batches is very good, and the quality control is great. Thank you!
  • 1***22019-10-12
    0People Like
    Human PD-L2 / B7-DC Protein, Fc Tag (MALS verified)
    I purchased the PD-L2 protein for ELISA related experiments. Coating the protein into a well plate, and then adding antibody molecules to incubate with biotin-PD1. I could obtain good stable and repeatable data.
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