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NGFR

NGFR Overview

English NameLow affinity neurotrophin receptor p75NTRApproved Drugs0
Drugs in Clinical Trials2Target SynonymGp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
Highest Development StagePhase 2 Clinical
English NameLow affinity neurotrophin receptor p75NTR
Target SynonymGp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
Approved Drugs0
Drugs in Clinical Trials2
Highest Development StagePhase 2 Clinical

NGFR Product List

  • Product Category

    Protein (1)Cell (1)

  • Product Status

    Launched (2)

  • Species

    Human (2)

  • Tag

    Fc Tag (1)- (1)

  • Conjugate

    Unconjugated (1)- (1)

Total: 2
  • 1

NGFR Background

The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins(NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.

NGFR Synonyms

tumor necrosis factor receptor superfamily member 16; CD271; Gp80-LNGFR; member 16 nerve growth factor receptor; p75 ICD; p75 NTR
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  • Product List