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Mesothelin

Mesothelin Overview

English NameMesothelinApproved Drugs0
Drugs in Clinical Trials45Target SynonymPre-pro-megakaryocyte-potentiating factor，Mesothelin，MSLN，CAK1 Antigen，MPF，Soluble MPF Mesothelin Related Protein，Megakaryocyte Potentiating Factor，SMRP，CAK1
Highest Development StagePhase 2 Clinical
English NameMesothelin
Target SynonymPre-pro-megakaryocyte-potentiating factor，Mesothelin，MSLN，CAK1 Antigen，MPF，Soluble MPF Mesothelin Related Protein，Megakaryocyte Potentiating Factor，SMRP，CAK1
Approved Drugs0
Drugs in Clinical Trials45
Highest Development StagePhase 2 Clinical

Mesothelin Product List

  • Product Category

    Protein (28)Beads (1)Cell Grade Beads (1)Cell (2)Kits (1)

  • Product Status

    Launched (33)

  • Species

    Human (28)Mouse (3)Cynomolgus (1)Rat (1)

  • Tag

    His Tag (17)Fc Tag (7)His Tag & Avi Tag (3)Fc Tag & Avi Tag (1)- (5)

  • Conjugate

    Unconjugated (9)Biotin-labeled (7)FITC Labeled (4)GFP Fusion (1)RFP Fusion (1)PE Labeled (2)- (4)APC Labeled (2)AF555 Labeled (1)AF647 Labeled (1)AF488 Labeled (1)

Total: 33
  • 1
  • 2
  • 3
  • 4

Mesothelin Background

Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.

Mesothelin Synonyms

MSLN,Mesothelin,MPF

Product Reviews

  • B***a2023-07-11
    0People Like
    APC-Labeled Human Mesothelin / MSLN (296-580) Protein, His TagStar Staining
    This is one of the only conjugated mesothelin proteins available on the market! It has great specificity for flow cytometry staining, this has been a game changer for us to measure human mesothelin present in our samples with an easy and quick one-step staining method. This is a great quality product and we will be ordering so many more in the future!
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