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GLP1R

GLP1R Overview

English NameGlucagon-like peptide-1Approved Drugs0
Drugs in Clinical Trials5Target SynonymGLP-1
Highest Development StagePhase 3 Clinical
English NameGlucagon-like peptide-1
Target SynonymGLP-1
Approved Drugs0
Drugs in Clinical Trials5
Highest Development StagePhase 3 Clinical

GLP1R Product List

  • Product Category

    Protein (6)Cell (5)

  • Product Status

    Launched (11)

  • Species

    Human (11)

  • Tag

    His Tag (1)His Tag & Avi Tag (1)Fc Tag (1)- (6)His Tag & Flag Tag (1)His Tag & Avi Tag & Flag Tag (1)

  • Conjugate

    Unconjugated (4)Biotin-labeled (2)- (5)

Total: 11
  • 1
  • 2

GLP1R Background

This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke.

GLP1R Synonyms

GLP-1-R, GLP-1R, glucagon like peptide 1 receptor
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  • Product List