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FcRn (FCGRT & B2M)

FcRn (FCGRT & B2M) Overview

English NameIgG receptor FcRn large subunit p51Approved Drugs3
Drugs in Clinical Trials2Target SynonymAlpha-Chain，FcRn，Major Histocompatibility Complex Class I-Like Fc Receptor，Immunoglobulin Receptor， Intestinal， Heavy Chain，Neonatal Fc-Receptor For Ig，FcRn Alpha Chain，FCGRT，IgG Fc fragment receptor transporter alpha chain，Neonatal Fc receptor，Fc Fragment Of IgG Receptor And Transporter，Transmembrane Alpha Chain Of The Neonatal Receptor，Fc Fragment Of IgG， Receptor， Transporter， Alpha，IgG receptor FcRn large subunit p51，Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor
Highest Development StageApproved
English NameIgG receptor FcRn large subunit p51
Target SynonymAlpha-Chain，FcRn，Major Histocompatibility Complex Class I-Like Fc Receptor，Immunoglobulin Receptor， Intestinal， Heavy Chain，Neonatal Fc-Receptor For Ig，FcRn Alpha Chain，FCGRT，IgG Fc fragment receptor transporter alpha chain，Neonatal Fc receptor，Fc Fragment Of IgG Receptor And Transporter，Transmembrane Alpha Chain Of The Neonatal Receptor，Fc Fragment Of IgG， Receptor， Transporter， Alpha，IgG receptor FcRn large subunit p51，Heavy Chain Of The Major Histocompatibility Complex Class I-Like Fc Receptor
Approved Drugs3
Drugs in Clinical Trials2
Highest Development StageApproved

FcRn (FCGRT & B2M) Product List

  • Product Category

    Protein (22)Cell (2)Kits (1)

  • Product Status

    Launched (25)

  • Species

    Human (9)Cynomolgus / Rhesus macaque (4)Rat (2)Mouse (4)Porcine (1)Feline (1)Rabbit (2)Canine (2)

  • Tag

    His Tag & Strep Tag (6)His Tag & Strep Tag & Avi Tag (3)His Tag & Avi Tag & Strep Tag (1)His Tag & Avi Tag (6)His Tag (5)- (3)Strep Tag (1)

  • Conjugate

    Unconjugated (11)Biotin-labeled (11)- (3)

Total: 25
  • 1
  • 2
  • 3

FcRn (FCGRT & B2M) Background

FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.

FcRn (FCGRT & B2M) Synonyms

FcRn,FCGRT & B2M

Product Reviews

  • N***i2024-12-24
    0People Like
    Biotinylated Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS&SPR verified)
    I recently used the Biotinylated Rabbit FcRn on the Biacore 8K+ and was highly impressed with its performance. The product worked perfectly as described, delivering reliable and consistent results. It also arrived within the expected time frame, which I greatly appreciated. Overall, I am very satisfied with the quality and service, and I would highly recommend this product to others
  • C***n2023-05-03
    1People Like
    Biotinylated Mouse FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™ (MALS & BLI verified)
    I used Acro's FcRn for development of novel assays. The proteins within just a few days of placing the order. The proteins were also high quality, stable, and did not result in any background in any of the assays that were developed, even after using them for months. These produced great data and we have continued to repurchase them since. I would highly recommend this product.
  • B***r2022-06-07
    0People Like
    Biotinylated Rabbit FcRn / FCGRT&B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS&SPR verified)
    Protein was received quickly and was high purity confirmed via HPLC, FPLC, SDS-PAGE. Biotinylation label was perfect and confirmed via streptavidin gel shift. Protein was primarily used for ELISA and FACS. Great experimental results so far. Also ordered multiple peptides to determine which domain is the best target. We are hoping to implement the results into our clinical study looking at how targeting the FcRn affects IgG and IgG IC.
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