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CXCL4

CXCL4 Overview

English NamePlatelet factor 4Approved Drugs0
Drugs in Clinical Trials0Target SynonymPF-4，C-X-C motif chemokine 4，CXCL4
Highest Development StagePreclinical
English NamePlatelet factor 4
Target SynonymPF-4，C-X-C motif chemokine 4，CXCL4
Approved Drugs0
Drugs in Clinical Trials0
Highest Development StagePreclinical

CXCL4 Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Total: 1
  • 1

CXCL4 Background

CXCL4, or Platelet factor 4 (PF4), is a small cytokine belonging to the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. CXCL4 is chemotactic for neutrophils and monocytes and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment.

CXCL4 Synonyms

PF4,CXCL4,MGC138298,SCYB4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A
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