Select Language
Free Registration

CD8 alpha

CD8 alpha Overview

English NameCluster of differentiation 8Approved Drugs0
Drugs in Clinical Trials14Target SynonymCD8 Antigens
Highest Development StagePhase 3 Clinical
English NameCluster of differentiation 8
Target SynonymCD8 Antigens
Approved Drugs0
Drugs in Clinical Trials14
Highest Development StagePhase 3 Clinical

CD8 alpha Product List

  • Product Category

    Protein (10)

  • Product Status

    Launched (10)

  • Species

    Mouse (2)Human (6)Cynomolgus (2)

  • Tag

    His Tag & Avi Tag (4)His Tag (5)Fc Tag (1)

  • Conjugate

    Biotin-labeled (3)Unconjugated (3)AF488 Labeled (3)AF647 Labeled (1)

Total: 10
  • 1

CD8 alpha Background

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

CD8 alpha Synonyms

CD8A,CD8,Leu2,MAL,p32
  • Overview
  • Product List