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CD5

CD5 Overview

English NameT-cell surface glycoprotein CD5Approved Drugs0
Drugs in Clinical Trials11Target SynonymEpididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens
Highest Development StagePhase 2 Clinical
English NameT-cell surface glycoprotein CD5
Target SynonymEpididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens
Approved Drugs0
Drugs in Clinical Trials11
Highest Development StagePhase 2 Clinical

CD5 Product List

  • Product Category

    Protein (16)Antibody (2)Kits (1)

  • Product Status

    Launched (19)

  • Species

    Human (13)Mouse (2)Rhesus macaque (3)Rabbit (1)

  • Tag

    His Tag (6)His Tag & Avi Tag (4)Fc Tag & Avi Tag (2)Fc Tag (4)- (3)

  • Conjugate

    Unconjugated (5)FITC Labeled (2)Biotin-labeled (6)PE Labeled (2)AF647 Labeled (1)AF488 Labeled (2)- (1)

Total: 19
  • 1
  • 2

CD5 Background

T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

CD5 Synonyms

CD5,LEU1
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