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CD44

CD44 Overview

English NameCD44 antigenApproved Drugs0
Drugs in Clinical Trials10Target SynonymHermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
Highest Development StagePhase 3 Clinical
English NameCD44 antigen
Target SynonymHermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
Approved Drugs0
Drugs in Clinical Trials10
Highest Development StagePhase 3 Clinical

CD44 Product List

  • Product Category

    Protein (2)Antibody (2)

  • Product Status

    Launched (4)

  • Species

    Human (2)Rabbit (1)Mouse (1)

  • Tag

    His Tag (1)Fc Tag (1)- (2)

  • Conjugate

    Unconjugated (3)PE Labeled (1)

Total: 4
  • 1

CD44 Background

CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

CD44 Synonyms

CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,Epican
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