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CD28

CD28 Overview

English NameT-cell-specific surface glycoprotein CD28Approved Drugs0
Drugs in Clinical Trials24Target SynonymCD28，CD28 Antigen，T-Cell-Specific Surface Glycoprotein CD28，CD28 Antigen (Tp44)，Tp44，CD28 Antigens，CD28 Molecule，T-Cell-Specific Surface Glycoprotein
Highest Development StagePhase 2 Clinical
English NameT-cell-specific surface glycoprotein CD28
Target SynonymCD28，CD28 Antigen，T-Cell-Specific Surface Glycoprotein CD28，CD28 Antigen (Tp44)，Tp44，CD28 Antigens，CD28 Molecule，T-Cell-Specific Surface Glycoprotein
Approved Drugs0
Drugs in Clinical Trials24
Highest Development StagePhase 2 Clinical

CD28 Product List

  • Product Category

    Protein (9)Antibody (5)Kits (1)

  • Product Status

    Launched (15)

  • Species

    Mouse (9)Human / Cynomolgus / Rhesus macaque (5)Rat (1)

  • Tag

    His Tag (3)Fc Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Fc Tag (2)His Tag & Avi Tag (2)Mouse IgG1 (1)- (5)

  • Conjugate

    Unconjugated (8)Biotin-labeled (4)- (1)PE Labeled (1)APC Labeled (1)

Total: 15
  • 1
  • 2

CD28 Background

T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

CD28 Synonyms

CD28,Tp44
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