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CD133

CD133 Overview

English NameCD133Approved Drugs0
Drugs in Clinical Trials1Target SynonymAntigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Highest Development StagePhase 2 Clinical
English NameCD133
Target SynonymAntigen AC133，Prominin-1，PROM1，Prominin 1，Prominin-Like Protein 1，PROML1，Stargardt Disease 4 (Autosomal Dominant)，Hematopoietic Stem Cell Antigen，Macular Dystrophy， Retinal 2，Prominin (Mouse)-Like 1，CD133 Antigen，HProminin，MSTP061，CORD12，AC133，CD133，MCDR2，STGD4，RP41，AC133 Antigen
Approved Drugs0
Drugs in Clinical Trials1
Highest Development StagePhase 2 Clinical

CD133 Product List

  • Product Category

    Protein (5)Cell (1)

  • Product Status

    Launched (5)In Research (1)

  • Species

    Human (5)Cynomolgus (1)

  • Tag

    His Tag (2)- (3)His Tag & Avi Tag (1)

  • Conjugate

    Unconjugated (3)Biotin-labeled (2)- (1)

Total: 6
  • 1

CD133 Background

Prominin-1 is also known as CD133, Antigen AC133, PROM1, PROML1 and MSTP061. Is used as marker for hematopoietic stem and progenitor cells (HSPC) for somatic stem cell isolation. May play a role in cell differentiation, proliferation and apoptosis . Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

CD133 Synonyms

CD133,PROM1,PROML1,Prominin-1,AC133
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