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ACHE

ACHE Overview

English NameAcetylcholinesteraseApproved Drugs27
Drugs in Clinical Trials26Target SynonymEC:3.1.1.7，EC 3.1.1，Acetylcholinesterase (YT Blood Group)，Acetylcholinesterase (Cartwright Blood Group)，Yt Blood Group，Apoptosis-Related Acetylcholinesterase，Acetylcholinesterase，EC 3.1.1.7，ARACHE，N-ACHE，ACEE，AChE，YT
Highest Development StageApproved
English NameAcetylcholinesterase
Target SynonymEC:3.1.1.7，EC 3.1.1，Acetylcholinesterase (YT Blood Group)，Acetylcholinesterase (Cartwright Blood Group)，Yt Blood Group，Apoptosis-Related Acetylcholinesterase，Acetylcholinesterase，EC 3.1.1.7，ARACHE，N-ACHE，ACEE，AChE，YT
Approved Drugs27
Drugs in Clinical Trials26
Highest Development StageApproved

ACHE Product List

  • Product Category

    Protein (1)

  • Product Status

    Launched (1)

  • Species

    Human (1)

  • Tag

    His Tag (1)

  • Conjugate

    Unconjugated (1)

Total: 1
  • 1

ACHE Background

The enzyme acetylcholinesterase, also known as AChE or acetylhydrolase, is the primary cholinesterase in the body. It is a serine hydrolase whose primary function is to catalyzes the breakdown of acetylcholine(ACh) and of some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. Acetylcholine deficit has been found in Alzheimer's disease (AD) ans is associated with cognetive decline. Therefore, AChE has been reported to be a viable therapeutic target for the treatment of AD and other dementias. To this end, acetylcholinesterase inhibitors (AChEIs) are commonly used.

ACHE Synonyms

acetylcholinesterase (Yt blood group),Acetylcholinesterase,ACHE,apoptosis-related acetylcholinesterase,ARACHE,EC 3.1.1,EC 3.1.1.7,N-ACHE,Yt blood group,YT
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