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Your Position: Home > Recombinant Antibodies > MMAE > MME-M5252

Mouse Anti-MMAE Antibody, Mouse IgG1

  • Source
    Monoclonal Anti-MMAE Antibody, Mouse IgG1 (MME-M5252) is expressed from human 293 cells.
  • Isotype
    Mouse IgG1 / kappa
  • Specificity
    Specifically recognizes the target-MMAE.
  • Application
    This Monoclonal anti-MMAE antibody is designed for use in ELISA and PK environment.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied and shipped as sterile liquid solution with dry ice, please inquire the shipping cost.
SDS-PAGE
Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) SDS-PAGE gel

Mouse Anti-MMAE Antibody, Mouse IgG1 on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. ) MALS images

The purity of Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) was more than 90% and the molecular weight of this protein is around 134-163 kDa verified by SEC-MALS.

Bioactivity-ELISA
Mouse Anti-MMAE Antibody, Mouse IgG1Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) ELISA bioactivity

Immobilized Disitamab Vedotin (RC48) at 1 μg/mL (100 μL/well) can bind Mouse Anti-MMAE Antibody, Mouse IgG1 (Cat. No. MME-M5252) with a linear range of 0.2-2 ng/mL (QC tested).

  • Background
    Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $300.00

Price(USD) : $1800.00

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